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By Abrams K.

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2. The hRRA/RIA ratio was better in the Laron syndrome patients than in the controls in whom the RIA values exceeded those found by the RRA. The dilution curves of the serum hGH from the Laron syndrome patients were parallel to the standard curve, denoting identical structure of the hGH at its binding sites. 3 Discussion Previous reports of quantitative comparison of the hGH values obtained with the RIA and RRA in acromegalic and normal subjects using rabbit liver receptors showed a systematic overestimation by RIA (Herington et al.

None of the Jewish families is Ashkenazi. The non-Jewish families comprise nine Arabs and one Druze; the additional ten families are from South-America, Italy, Greece, Malta, and Malaysia. 2 Distribution of Ethnic origins in the Israeli cohort of Laron syndrome patients Total number of No. of patients (M: F) families 64a (33 : 31) Jews of oriental origin 31a (13 : 18) Iran – 11 Iraq – 7 Yemen – 2 Morocco – 1 Afghanistan – 1 16 (11 : 5) Arabs (including Israelis, Palestinians, and others) Moslems – 6 Christians – 1 Druze 1F Druze – 1 Malaysia 2M Moslems – 2 Other ethnic origins (from: South America, Italy, Greece, Malta) 14 (7 : 7) Maronite – 1 Including four deceased a described in Laron et al.

Horm Res 22:276–283 Golde DW, Bersch N, Kaplan SA, Rimolin DL, Li CH (1980) Peripheral unresponsiveness to human growth hormone in Laron dwarfism. N Engl J Med 303:1156–1159 Hartman ML (2000) Physiological regulators of growth hormone secretion. In: Juul A, Jorgensen JOL (eds) Growth hormone in adults, 2nd edn. Cambridge University Press, Cambridge, pp 3–53 Herington AC, Jacobs LS, Daughaday WH (1974) Radioreceptor and radioimmunoassay quantitation of human growth ­hormone in acromegalic serum: overestimation by immunoassay and systematic differences between antisera.

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A Bayesian Approach to Weibull Survival Models - Application to a Cancer Clinical Trial by Abrams K.

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